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Please contact us for more information

Email: contact@holodiag.com
Phone: +33(0)
Fax: +33(0)

Our strengths

  • - swift processing
  • - elaborated report
  • - expertise of our team

Acidic and basic moieties are widespread among pharmaceutical molecules. Measurements of pKa values are thus essential for the development of crystallization processes. It ensures the stability of the API by mastering the pH. It is also a necessary step for the formation of salts (c.f. our activities of salt selection and resolving agents).


Holodiag performs pKa measurements in aqueous solutions, in water / organic solvent mixes as well as in pure organic solvents. Data can then be extrapolated to aqueous solutions if needed.

Information and cost

Should you need more details or a quotation, please contact us.

Our analytical services are carried out under 5 worked days and come with a bibliographic search (patents, publications, crystal structures, ...) as well as an elaborated report that answer your concerns. Besides, our team remains available by phone and/or email for any additional detail or information you could further need .