Please contact us for more information
- - elaborated report
- - swift processing
- - expertise of our team
Polymorphism is the ability for a molecule to crystallize under several solid forms (packings). This phenomenon virtually concerns every solid form and represents a major stake in the pharmaceutical industry because of its impact on patents, DMF and market authorizations, business strategy, ...
Ignoring polymorphism entails you to dramatic consequences from a simple delay in the study to the cancellation of the development project.
Holodiag gives you the control of the polymorphism of your API:
- bibliographic synthesis, state of the art concerning known forms
- polymorphism screening, form identification
- polymorphism study: relative stability (with respect to temperature, relative humidity, solvent composition), solid phase transformations, solubility profiles, choice of the most appropriate form, ...
- development of robust crystallization processes, identification of critical parameters with the aim of process industrialization
Activity tracking and reporting
Scheduled reporting and steering committees allow you a real-time monitoring of the studies. Besides, Holodiag delivers a high quality report which is a tool in the decision making process. This report highlights the key points together with advices for further development steps.
Information and cost
Should you need more details or a quotation, please contact us.